Genetic+Engineering

http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter16/animations.html# http://sciencevideos.wordpress.com/category/genetic-engineering/ http://www.animate4.com/genetic-gene-therapy.htm http://www.cartoonstock.com/animation/directory/g/genetic_engineering_animations.aspmedia type="youtube" key="AEINuCL-5wc" width="425" height="350"media type="youtube" key="teV62zrm2P0" width="425" height="350"media type="youtube" key="NJxobgkPEAo" width="425" height="350"

http://www.phschool.com/science/biology_place/biocoach/red/mapping.html
 * REFER THIS SITE FOR ILLUSTRATIONS**

DNA is a right-handed double helix.
 * Concept 1: The DNA Helix**

Restriction enzymes are found naturally mostly in bacteria. In this figure, DNA is shown in pink as a space-filled helix. The two symmetrical domains of the restriction endonuclease, EcoRI, are shown in blue and yellow.
 * Concept 2: Ribbon Model of Restriction Enzyme**

DNA may be analyzed by gel electrophoresis. In this process, DNA molecules migrate to the + pole as a current passes through the gel.
 * Concept 3: Analysis of DNA by Gel Electrophoresis**

Suppose we have a circular DNA molecule, called pTut (for "tutorial"), that is 7666 bp (7.666 kbp) long. (1 kbp = 1 kilobase pair = 1000 base pairs.) The assignment is to prepare a restriction map for the sites for the enzymes BglII, BstEII, and EcoRV. This map will show the locations of the cutting sites of the three enzymes with respect to one another.
 * Concept 4: A Hypothetical (Tutorial) DNA Mapping Example**

http://www.phschool.com/science/biology_place/biocoach/red/quiz.html

Since the Human Genome Project, up to 20% of human genes have been patented by their discoverers. By patenting the genes – which are present in all of us – the companies responsible have control over what can be done with regards to research, diagnostic testing and treatment. Recently, one company’s patent of the BRCA1 gene was overturned, opening the doors to research with reduced legal worries. Read this neat article from BadScience: “I patent your ass. And your leg…“ Here is a short video on the BRCA1 gene (critical in women), from OvarianCancerDr:

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Questions: 1. What was the effect of the patent on research and medicine? 2. What is the effect of the patent being overturned now likely to be? 3. Explain the significance of the clause that states “

[|Quiz on Cloning from Discovery Channel]

[|DNA Cut & Paste activity]